An herbal extract inhibits the development of pancreatic cancer (Philadelphia)An
herb recently found to kill pancreatic cancer cells also appears to inhibit
development of pancreatic cancer as a result of its antiinflammatory properties,
according to researchers from the kimmel cancer center at jefferson.The data
were presented at the aacr 100th annual meeting 2009 in denver. beats by dre
sale online Nigella sativa seeds and oil are used in traditional
medicine by many middle eastern and asian countries.It helps treat a broad array
of diseases, including some immune and inflammatory disorders, dr.Arafat
said.Thymoquinone almost completely abolished the expression of several
inflammatory cytokines, including tnfalpha, interleukin1beta, interleukin8, cox2
and mcp1, an effect that was more superior to the effect of trichostatin a. The
herb also inhibited the activation and synthesis of nfkappab, a transcription
factor that has been implicated in inflammationassociated cancer.Activation of
nfkappab has been observed in pancreatic cancer and may be a factor in
pancreatic cancer's resistance to chemotherapeutic agents.When animal models of
pancreatic cancer were treated with thymoquinone, 67 percent of the tumors were
significantly shrunken, and the levels of proinflammatory cytokines in the
tumors were significantly reduced. Inflammation has been implicated in the beats by dre
outlet development of several solid tumor malignancies.Chronic
pancreatitis, both hereditary and sporadic, is associated with the risk of
developing pancreatic cancer. "These are very exciting and novel
results,"Dr.Arafat said. "Not only patients with chronic pancreatitis could
benefit from this, but also several other groups with risk of development or
recurrence of pancreatic cancer, such as highrisk family members and
postsurgical patients.These potent effects show promise for the herb as a
potential preventive and therapeutic strategy for pancreatic cancer.More
importantly, the herb and oil are safe when used btsbydreuale moderately, and have
been used for thousands of years without reported toxic effects. "Pancreatic
cancer is the fourth leading cause of cancer death in the united states, with
approximately 32, 000 deaths a year.Only five percent of individuals with
pancreatic cancer live for at least one year after diagnosis.
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